I made a pretty radical change last hunting season that may be of interest to some:
For the last 15 years my set-up was 100-gr Rocket Hammerhead expandables with a total arrow weight of 425 grains. I've harvested about 35 deer with this set-up, using my 2001-vintage Exocet. Velocity is 273 fps.
Last hunting season I switched to Centaur Battleaxe Broadheads. These are enormous, 242-gr two-blade, single-bevel fixed-blade heads that appear ridiculously over-sized at 2 inches wide. And my total arrow weight now is 577 grains! Velocity is 249 fps.
Sounds (and looks) crazy, but by fletching with 2" Blazers or Quickspins at the maximum LW Helical that my fletching jig allows, these over-sized heads actually group with field points out to 40 yards.
I took three deer with these last season. I got complete pass-throughs in every case, no matter what bones were hit. In one case the pass-through was length-wise! And the blood trail is instant and profuse.
I now can do straight-down spine shots at deer directly under my stand and get a pass-through heart shot. I could never risk that shot with a conventional expandable broadhead.